A literature search disclosed only very limited published material suggesting that EDTA therapy when given slowly does not seem to derange serum calcium metabolism. This report summarizes the observations of eighty private practice patients treated with EDTA and supportive multivitamin/trace mineral supplementation and its effects upon serum calcium. The evidence indicates that, in general, this form of chelation therapy does not alter serum calcium concentration. Additionally, and perhaps more importantly, the evidence here suggests the so-called high normals declined slightly, the low normals rise slightly, and those in the intermediate range remain unchanged.
E. W. McDonagh, C. J. Rudolph and E. Cheraskin
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